By: 16 November 2017
ReproBone® fusion – Injectable multiphasic matrix for bone regeneration

ReproBone fusion bone graft substitute is an innovative, synthetic fusion of hydroxyapatite/tri-calcium phosphate granules in an osteostimulative carrier. This high-quality biomaterial is manufactured in the UK and is a non-setting, injectable matrix that combines the early stimulating activity of nano-structured hydroxyapatite with the longer-term support of a highly porous micro-scaffold.


Stimulate – Integrate – Regenerate

ReproBone fusion is indicated for use as a bone graft substitute for the repair of non-load bearing aseptic osseous defects. Its mouldable and firm texture is especially suitable for the filling of spinal fusion cages or bone defects that require longer-term support and volume stability.

ReproBone fusion comes ready to use in a prefilled syringe. Its volume stable viscosity allows easy and accurate application of the granulated paste. Excellent contact with the viable bone surface maximises the bone implant interface. The non-setting formula supports bone regeneration by encouraging rapid cell ingrowth throughout the healing process.

ReproBone fusion’s enhanced activity profile from the unique multiphase composition of nano, micro and macro structured material supports and encourages formation of new bone while maintaining volume. Over time the material is gradually replaced by mature bone.

ReproBone fusion’s highly active matrix attracts and absorbs biomolecules on to the surface to create a stimulatory microenvironment that
promotes new bone formation.


Ceramisys Ltd

T: +44 (0) 114 232 7070